Thursday, August 7, 2008

[EQ] Health Partnerships Review: Focusing collaborative efforts on research and innovation for the health of the poor

Health Partnerships Review

Focusing collaborative e­ orts on research and innovation for the health of the poor

 

Global Forum for Health Research 2008

 

Available online as PDF file [102p.] at: http://www.globalforumhealth.org/filesupld/hpr/HealthPartnershipsReview_Full.pdf

 

“The poor die young. Data from every part of the world show that, whether comparing richer and poorer populations within or between countries, those that are least well off have shorter life expectancies and heavier burdens of disease than those that are relatively wealthy. While the highest attainable standard of health has been declared  a human right, this health inequity reflects a collective neglect at national and global levels – neglect of diseases, of health systems and ultimately of people….”


“….Three areas of failure can be highlighted that represent different dimensions of the problem – failures of science (where basic knowledge or tools are lacking), failures of the market (where economic incentives for the production of needed medicines are lacking), and public health failures (where systems and programmes to implement available interventions are lacking)….”
From Stephen Matlin, Executive Director, Global Forum for Health Research

 

“…..Over the last few years, partnerships between public and private sector organizations have become an increasingly common mechanism to address some of the diseases of the poor in developing countries.

The ultimate goal of most of these partnerships is to improve and increase access to treatment, particularly for ‘neglected diseases’. Many also express the goal of contributing to the alleviation of poverty through improved health.

The need for such partnerships can be explained by a failure of public health systems – the inability of the public sector to provide public goods entirely on its own, due to lack of resources; competing priorities for the limited resources available; management issues; conflict and post-conflict situations; etc. There is also a failure on the part of the private sector when there is little or no commercial incentive for the development of diagnostics and medicines for most of the diseases endemic in developing countries and affecting mainly the very poor…”

 

Contents


Foreword  Stephen Matlin


Focusing collaborative efforts on research and innovation for the health of the poor

The PDP approach


The new landscape of product development partnerships (PDPs)

Stefanie Meredith and Elizabeth Ziemba


Public–private partnerships in health systems -
Sania Nishtar

 
Issues in assessing product development partnerships (PDPs) -
Lakshmi Sundaram

 
Technological and social innovation: a unifying new paradigm for global health

Charles A Gardner, Tara Acharya and Derek Yach

 
Product development partnerships: public–private partnerships among unequal partners?

Anna Wang

 

 
Research and development

Facing the dual challenge of developing both products and research capacities for neglected diseases

Piero L Olliaro and Stephen C Wayling

 
The portfolio approach to successful product development in global health -
David Brown


The role of the health system in biotechnology in Brazil and Cuba -
Halla Thorsteinsdóttir


Sustainable (vaccine) development: the International AIDS Vaccine Initiative (IAVI) and capacity building

Joanna Chataway and Rebecca Hanlin


Beyond market failures: IAVI and the organizational challenges of vaccine development

Luigi Orsenigo, Stefano Brusoni and Eugenia Cacciatori

 

    
Clinical trials

Clinical trial site capacity for malaria product development

Mary Moran, Javier Guzman, Anne-Laure Ropars, Margaret Jorgensen, Sarah Potter, Alina McDonald and Hiwot Haile-Selassie


Issues surrounding the implementation of multiple product development partnership clinical trials in developing countries

Gita Ramjee


Collaborative approach to clinical trials -
Charles S Mgone and Pascoal Mocumbi


Running clinical trials in partnership with communities -
Anjali Gopalan

 

Bringing products to market

Getting diagnostics into countries - Vinand M Nantulya


The control of neglected tropical diseases using access to available medicines through public–private partnerships

Alan Fenwick, Peter J Hotez and David H Molyneux


The story of ASAQ: the first antimalarial product development partnership success

Bernard Pécoul, Ann-Marie Sevcsik, John Amuasi, Graciela Diap and Jean-René Kiechel


Managing intellectual property for global health outcomes: the example of product development partnerships

Robert Eiss


Regulatory strategies of product development partnerships: some perspectives

Chris Hentschel, Jörg Möhrle and Jaya Banerji

 

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