Health Partnerships Review
Focusing collaborative e orts on research and innovation for the health of the poor
Global Forum for Health Research 2008
Available online as PDF file [102p.] at: http://www.globalforumhealth.org/filesupld/hpr/HealthPartnershipsReview_Full.pdf
“The poor die young. Data from every part of the world show that, whether comparing richer and poorer populations within or between countries, those that are least well off have shorter life expectancies and heavier burdens of disease than those that are relatively wealthy. While the highest attainable standard of health has been declared a human right, this health inequity reflects a collective neglect at national and global levels – neglect of diseases, of health systems and ultimately of people….”
“….Three areas of failure can be highlighted that represent different dimensions of the problem – failures of science (where basic knowledge or tools are lacking), failures of the market (where economic incentives for the production of needed medicines are lacking), and public health failures (where systems and programmes to implement available interventions are lacking)….” From Stephen Matlin, Executive Director, Global Forum for Health Research
“…..Over the last few years, partnerships between public and private sector organizations have become an increasingly common mechanism to address some of the diseases of the poor in developing countries.
The ultimate goal of most of these partnerships is to improve and increase access to treatment, particularly for ‘neglected diseases’. Many also express the goal of contributing to the alleviation of poverty through improved health.
The need for such partnerships can be explained by a failure of public health systems – the inability of the public sector to provide public goods entirely on its own, due to lack of resources; competing priorities for the limited resources available; management issues; conflict and post-conflict situations; etc. There is also a failure on the part of the private sector when there is little or no commercial incentive for the development of diagnostics and medicines for most of the diseases endemic in developing countries and affecting mainly the very poor…”
Contents
Foreword Stephen Matlin
Focusing collaborative efforts on research and innovation for the health of the poor
The PDP approach
The new landscape of product development partnerships (PDPs)
Stefanie Meredith and Elizabeth Ziemba
Public–private partnerships in health systems - Sania Nishtar
Issues in assessing product development partnerships (PDPs) - Lakshmi Sundaram
Technological and social innovation: a unifying new paradigm for global health
Charles A Gardner, Tara Acharya and Derek Yach
Product development partnerships: public–private partnerships among unequal partners?
Anna Wang
Research and development
Facing the dual challenge of developing both products and research capacities for neglected diseases
Piero L Olliaro and Stephen C Wayling
The portfolio approach to successful product development in global health - David Brown
The role of the health system in biotechnology in
Sustainable (vaccine) development: the International AIDS Vaccine Initiative (IAVI) and capacity building
Joanna Chataway and Rebecca Hanlin
Beyond market failures: IAVI and the organizational challenges of vaccine development
Luigi Orsenigo, Stefano Brusoni and Eugenia Cacciatori
Clinical trials
Clinical trial site capacity for malaria product development
Mary Moran, Javier Guzman, Anne-Laure Ropars, Margaret Jorgensen, Sarah Potter, Alina McDonald and Hiwot Haile-Selassie
Issues surrounding the implementation of multiple product development partnership clinical trials in developing countries
Gita Ramjee
Collaborative approach to clinical trials - Charles S Mgone and Pascoal Mocumbi
Running clinical trials in partnership with communities - Anjali Gopalan
Bringing products to market
Getting diagnostics into countries - Vinand M Nantulya
The control of neglected tropical diseases using access to available medicines through public–private partnerships
Alan Fenwick, Peter J Hotez and David H Molyneux
The story of ASAQ: the first antimalarial product development partnership success
Bernard Pécoul, Ann-Marie Sevcsik, John Amuasi, Graciela Diap and Jean-René Kiechel
Managing intellectual property for global health outcomes: the example of product development partnerships
Robert Eiss
Regulatory strategies of product development partnerships: some perspectives
Chris Hentschel, Jörg Möhrle and Jaya Banerji
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