Survival and mortality of people infected with HIV in low and middle income countries:
results from the extended ALPHA network
AIDS:Volume 21 Suppl 6 November 2007p S1-S4
Ghys, Peter Da; Żaba, Basiab,c; Prins, Mariad,e
From the aJoint United Nations Programme on AIDS,
bLondon
cNational Institute for Medical Research,
dPublic Health Service,
eAcademic Medical Center (CINIMA),
The Entebbe workshop on analysis of survival post-infection
“…..Published at a time when antiretroviral treatment (ART) is rapidly being scaled up in most low and middle income countries [2], this collection of papers represents a major collaborative effort to quantify and analyse the survival from HIV seroconversion to death in the absence of ART. The advent of effective treatment means it will not be possible to conduct any further studies of this nature in the future, so the results from these analyses together with a small number of previously published survival studies will serve as a baseline against which to assess the impact of ART in low and middle income countries. In addition, this new information is important for deriving parameters to model HIV epidemics.
Several papers examine the survival period from seroconversion to death, before ART became available in the study sites. Figure 1 shows the geographical spread of the study sites represented. Most of these studies were conducted in Africa, including three community-based studies in Kisesa, Tanzania [3], Rakai, Uganda [4], and Masaka, Uganda [5], and one among pregnant women recruited at an antenatal clinic in Kigali, Rwanda [6]. Two studies were conducted in Thailand, one among military recruits [7] and one among blood donors and their partners [8].
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